Block.splsda - DIABLO - correlation between samples and variables

Analysis
1

Hi,

Is there any way to extract the association between samples (Y) and selected variables (biomarkers) ? like what we get in case of splsda?

Thanks a lot and looking forward

2

hi @nomranian,

It depends on the method you use. We have created a biplot for PCA and PLS.
Otherwise, we usually inspect the correlation circle plot in parallel with the sample plot to work out the associations.

Kim-Anh

3

Hi @kim-anh
Thanks a lot for your response.
I did the DIABLO analysis and I get as a network only association between the entities but not between entities and samples like what I could get from splsda.

I appreciate a lot your help.

4

hi @nomranian,

I am not sure which output you are referring to for DIABLO to extract the association between samples and variables. As I said earlier, you can examine the correlation circle plots AND the sample plots co-jointly to infer some associations. You can have a look at this vignette for a basic example on PCA and apply the same principles for the other methods (section 3.2): 3 PCA on the multidrug study | mixOmics vignette

You can also have a look at the example for N-integration and see if there is any output that you fancy.

Kim-Anh