My project is about predicting, with transcriptional data (X), a disease severity score (Y).
I performed an sPLS that I optimize with the perf function.
The final 25 genes I have in my 2 first components seem to well represent the severity score in plotindiv function.
But when I performed plotVar function, my variables don’t look strongly correlated to my severity score.
Is there something I don’t understand or I did not do well in my analyses ?
Thanks a lot for your help.