Thank you for creating the mixomics package, it has been really helpful in multiomics analysis. I was wondering if there was a way of projecting new samples into an existing splsda space. Let me develop the question:
We have a sample processing methodology that is supposed to enrich for cancer derived CNV. Each patient that we analyze ends up being divided into four different samples and only one of them should be more “cancer like”. In adittion, I have CNV data (read counts) from both healthy patients and cancer patients as my positive and negative controls. I performed both a pca and a splsda on the controls to select for cancer specific differences. The cluster perfectly without the need of many features. Now I would like to project the patients that we processed into the splsda space that I created with my controls. What I’m expecting is that the more “cancer like” samples will cluster closer to the cancer controls compared to the other three. Is there a way to do something along these lines?
Thanks, sorry if the question is a bit confusing.