Hello everyone ,
i have a question regarding the usage of the method of cross validation in spls , i am studying proteomic / metabolomic data across only 10 samples for the proteins i have up to 1433 proteins and for the metabolites i have up to 83 metabolites , i used loo (leave on out ) as cross validation method but the method end up selecting extreme numbers for proteins that is 1180 and for metabolites 80 , these numbers are unfortunately very hard to analyze , what can i do ? should i change the list keep X and Y values ( i usually select almost all the data set in these lists ) or should i move to Mfold ?
Thanks